منابع مشابه
Lipoplatin Formulation Review Article
Patented platform technologies have been used for the liposomal encapsulation of cisplatin (Lipoplatin) into tumor-targeted 110 nm (in diameter) nanoparticles. The molecular mechanisms, preclinical and clinical data concerning lipoplatin, are reviewed here. Lipoplatin has been successfully administered in three randomized Phase II and III clinical trials. The clinical data mainly include non-sm...
متن کاملPreclinical evaluation of a new liposomal formulation of cisplatin, lipoplatin, to treat cisplatin-resistant cervical cancer.
OBJECTIVE Cisplatin-based chemotherapy has been shown to improve survival in cervical cancer; however, treatment is associated with tumor resistance and significant toxicity. Lipoplatin is a new liposomal formulation of cisplatin, developed to reduce cisplatin toxicity, to improve drug accumulation at tumor sites and to overcome drug resistance. The aim of this study is to analyze the antitumor...
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Plasmapheresis, which is defined as the removal of plasma, can be either "adjusted plasma" or “exchange of plasma”. The former is defined as selective withdrawal of certain (un)-pathological plasma components in different ways such as perfusion and then returning the remained donor plasma to him, the latter is non-selective removal of all components of plasma to provide blood products for injec...
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During the past 50 years, growth and differentiation molecules have been identified and shown to contribute importantly to many different biological functions. One of these, the recently discovered neuregulin (NRG) and the associated erbB receptors were first found to be important for differentiation of the peripheral nervous system, where they direct the differentiation of Schwann cells from n...
متن کاملReview Article
Embryos of different species of vertebrate share a common organisation and often look similar. Adult differences among species become more apparent through divergence at later stages. Some authors have suggested that members of most or all vertebrate clades pass through a virtually identical, conserved stage. This idea was promoted by Haeckel, and has recently been revived in the context of cla...
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ژورنال
عنوان ژورنال: Journal of Drug Delivery
سال: 2012
ISSN: 2090-3014,2090-3022
DOI: 10.1155/2012/581363